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For more information after Sept 1, please contact Chair Jim Hungerford at this hotmail address James_Hungerford@hotmail.com Sunday, September 11, 2005. Official Methods Board - Study Director Workshop Sunday, September 11, 2005. Natural Toxins and Allergens Committee Meeting Monday, September 12, 2005, Morning: Opening of the Annual Meeting with Keynote Talk (not on toxins). Also awards ceremony. I recommend that you attend this even though it is not part of our toxin activities.
Monday Afternoon, September 12, 2005: 1:00 PM 4:30 PM Wiley Award. Monday Afternoon, September 12, 2005: 2:00 PM 5:00 PM, Tuesday (All day) September 13, 2005, 8:30 AM 4:30 PM. * There is a break during the Wiley Award Symposium at 3:10 p.m. 3:30 p.m. and posters can again be viewed 4:30 PM 5:00 PM. We apologize for the overlap between the toxin presentations of the Wiley Award Symposium and the Poster Presentations on Marine and Freshwater Toxins - We tried to have this changed but other scheduling issues intervened.
Wednesday Afternoon and Early Evening September 14, 2005, 1 PM 6 PM. Subgroups on Brevetoxins (NSP), Ciguatoxins, Cyanobacterial Toxins, Domoic Acids and Saxitoxins by LC, Saxitoxin Assays, and Yessotoxins. Also open to those interested in activities of the group besides the Task Force itself. MONDAY September 12, 2005, Schedule of Presentations Wiley Award Symposium Symposium Chair - Denise LeBlanc, Director of Research Support, National Research Council Canada, Institute for Marine Biosciences, Halifax, Nova Scotia, Canada 1:00 p.m. 1:40 p.m. Wiley Award Lecture: The Hunt for Red Tide Toxins: New Toxins, New Technologies Michael Quilliam, Recipient of 2005 Wiley Award, and Senior Research Officer, National Research Council Canada, Institute for Marine Biosciences 1:40 p.m. 2:10 p.m. Denise M. LeBlanc National Research Council, Nova Scotia, Canada 2:10 p.m. 2:40 p.m. Patrick T. Holland, Cawthron Institute, Nelson, New Zealand 2:40 p.m. 3:10 p.m. Maurice V. Laycock, Halifax, Nova Scotia, Canada 3:10 p.m. 3:30 p.m. 3:30 p.m. 4:00 p.m. Philipp Hess, Marine Institute, Galway, Ireland 4:00 p.m. 4:30 p.m. Hans P. Van Egmond, National Institute for Public Health and the Environment, Bilthoven, The Netherlands TUESDAY September 13, 2005, Schedule of Presentations 8:30 a.m. 11:30 a.m. Grand Ballroom 4-6 Symposium: Marine and Freshwater Toxins Community Quality Methods for Public Health and International Trade, Session 1 of 2 Symposium Co-Chair - James Hungerford, U.S. Food and Drug Administration, Bothell, Washington, USA 8:35 a.m. - 8:55 a.m. Richard J. Lewis, Institute for Molecular Bioscience, the University of Queensland, Queensland, Australia 8:55 a.m. - 9:15 a.m. Mark Poli, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA 9:15 a.m. - 9:35 a.m. Robert W. Dickey, Gulf Coast Seafood Laboratory, U.S. Food and Drug Administration, Dauphin Island, Alabama, USA 9:35 a.m. - 9:55 a.m. Lyn R. Briggs, AgResearch, Hamilton, New Zealand 9:55 a.m. 10:20 a.m. 10:20 a.m. - 10:40 a.m. Jerome Naar, Center for Marine Science, University of North Carolina at Wilmington, Wilmington, North Carolina, USA 10:40 a.m. - 11:00 a.m. Tore Aune, Norwegian School of Veterinary Science, Oslo, Norway 11:00 a.m. - 11:20 a.m. Toshiyuki Suzuki, Tohoku National Fisheries Research Institute, Miyagi, Japan 1:30 p.m. 4:30 p.m. -- Grand Ballroom 4-6 Symposium Co-Chair - James Hungerford, U.S. Food and Drug Administration, Bothell, Washington, USA 1:30 p.m. - 1:50 p.m Frances M. Van Dolah,Marine Biotoxins Program, NOAA National Ocean Service, Charleston, South Carolina, USA 1:50 p.m. - 2:10 p.m. Sherwood Hall, Washington Seafood Laboratory, Division of Science and Applied Technology, Office of Seafood, CFSAN, U.S. Food Drug Administration, Laurel, Maryland, USA 2:10 p.m. - 2:30 p.m. Lyndon E. Llewellyn, Australian Institute of Marine Science, Townsville, Australia 2:30 p.m. - 2:50 p.m. Armah A. De La Cruz, U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Cincinnati, Ohio, USA 2:50 p.m. 3:10 p.m. 3:10 p.m. - 3:30 p.m. 3:30 p.m. - 3:50 p.m. Ambrose Furey, Mass Spectrometry Centre for Proteomics and Biotoxin Research, Department of Chemistry, Cork Institute of Technology, Cork, Ireland 3:50 p.m. - 4:10 p.m. Jussi A. O. Meriluoto, Abo Akademi University, Turku, Finland 4:10 p.m.-4:30 p.m. Closing, Questions, Announcements Wiley Symposium Abstract: Shellfish toxins present a serious problem for public health and the economic well-being of the aquaculture industry. Extensive monitoring programs are required but the problem is a difficult one for the analytical chemist. Toxins range from polar, low molecular weight compounds to high molecular weight, lipophilic substances. Most are thermally labile and some are sensitive to pH, oxygen and light. Sensitive analytical methods that provide low (ppb) detection limits are required to provide adequate protection, and the techniques used must provide high-resolution separations and/or high detection selectivity to deal with complicated sample matrices. A contaminated sample may not only contain several toxin analogues from within one class but even several different classes of toxins. Furthermore, toxins may also be metabolically transformed in shellfish, which further complicates the analysis. This symposium will highlight some new analytical technologies that can be used in routine monitoring programs. The talks will present sophisticated techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS), as well as simple, rapid screening assays. The strict requirements for validation of such methods for regulatory work will also be discussed, along with the need and availability of certified reference materials (CRMs). Toxin Symposium Abstract: Sustained efforts are required to move marine and freshwater toxin monitoring into the 21st century. Our analytical tools must be updated and validated, and public health and international trade considerations are prime considerations in such efforts. The stakes are high since toxins, whether tropical or temperate in their distribution, hepatotoxic or paralytic in their action, cause substantial public health impact and financial loss. The challenges are also great. Many are potent neurotoxins and some are so toxic that they must be detected at ultra trace levels. For others additional challenges arise because the mechanism of toxicity is not yet well understood. In nearly all cases the causative micro plankton and other microorganisms are found in multiple locations around the globe. Detection methods for these toxins can be as numerous and varied as the toxins themselves. Functional methods respond, hopefully, in a toxin-mechanistic manner and could parallel health risk in the ideal case. Instrumental methods based on separations including powerful LC-MS techniques provide extreme detail, revealing toxin multiplicity from new congeners to metabolites. Such widely varying analytical technologies require very different approaches to their optimization and consideration as proposed replacements for existing monitoring tools, which are often archaic live animal bioassays. Yet what these share in common is a need to protect public health while still being stakeholder-friendly and economically-friendly. This symposium will address the development and validation of analytical methods for marine and freshwater toxins. In this, the talks will sometimes lean into other fields such as toxicology, pharmacology, risk-assessment, and other diverse areas besides analytical chemistry. The focus and final targets of these efforts however are the production of quality validated methods for marine and freshwater toxins. Topic areas will range from tropical toxins such as the brevetoxins and ciguatoxins, to other (and more widespread) temperate lipophilic toxins, to likewise ubiquitous saxitoxins, domoic acids, and cyanobacterial toxins. This symposium, and this year's associated Wiley Award symposium, will enhance and in turn benefit from discussions, collaborations, and other activities of the Marine and Freshwater Toxins Task Force. WENESDAY September 14, 2005, Task Force and Subgroup Meetings, 1 PM-6PM In scheduling, The Task Force chair will emphasize the subgroups in time allotment, with less than a half hour used for general Task Force discussions. At this time we do plan to hold the Cyanobacterial Toxins subgroup last, since the chair of this subgroup has a schedule conflict earlier in the afternoon. Other than that, at this time we do not have a firm schedule yet for the specific timing of individual sessions. On the website and forum ( in this specific location of the schedule text) I will post updates giving more detailed information when it is known. Rest assured there will be no parallel sessions so that all subgroups will be accessible to attendees.
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