Draft SMPRs in Development for Detection of Food Allergens by Rapid Methods

The ISPAM Working Group on Food Allergen Assays is developing draft Standard Method Performance Requirements (SMPRs®) for the rapid detection of priority food allergens.

The project is initially being supported by the AOAC Research Institute. The working group can continue its work with support of AOAC Organizational Affiliates (OAs) through the AOAC working group initiative.

 Standards development activities for the rapid detection of priority food allergens began in September 2016 during the AOAC Annual Meeting, with stakeholder endorsement of two fitness-for-purpose statements. Participants included representatives from conformity assessment, contract research organizations, food allergens, food and beverage, technology providers, regulators, and researchers, among others. Much interest and participation also came from members of the AOAC Food Allergens Community.

As recommended by the ISPAM Working Group on Food Allergen Assays, co-chaired by Samuel Godefroy (Université Laval) and Jupiter Yeung (Nestlé and co-chair of the AOAC Food Allergens Community) and endorsed by ISPAM, methods are needed for:

(1) Quantitative analysis of eggs, milk, tree nuts (almond, hazelnut), and peanuts in environmental samples and foods by ELISA-based technologies

(2) Detection of eggs, milk, tree nuts (almond, hazelnut), and peanuts in environmental samples and foods by ELISA-based technologies

ISPAM identified egg, milk, tree nuts (almond, hazelnut), peanut, and celery and mustard (emerging allergens) as priority allergens in need of standards development.

Based on fitness-for-purpose, the working group is developing draft SMPRs, focusing first on quantitative methods for egg using ELISA/Ligand-based analytical approaches. 

The working group has met twice and formulated an initial draft of an SMPR for quantitative methods for egg using ELISA and ligand-based approaches.  Based on the many initial comments received after the working group met twice by teleconference, it was decided to hold a core drafting team meeting at AOAC headquarters on February 3, 2017, in order to address the comments.  This will be followed by a meeting of the core drafting team on March 13, 2017, in conjunction with the AOAC Mid-year meeting, to progress on the consensus Draft SMPR.  On March 14, 2017, the co-chairs will present the progress achieved to the International Stakeholder Panel on Alternative Methods (ISPAM) and the entire Food Allergen Working Group, and make further adjustments to the Draft SMPR as recommended.

Subsequently, the Working Group will continue to refine the Draft SMPR until ready for posting on  the AOAC website for an open public comment period. All interested parties will be encouraged to submit comments. Comments will be compiled and reviewed, and the SMPRs revised, if necessary, based on the comments received

During the AOAC Annual Meeting in Atlanta Georgia, September 24 – 27, 2017, draft SMPRs will be presented to ISPAM, chaired by Erin Crowley of Q Laboratories, Inc., along with any comments received and how the comments were reconciled in an effort to reach consensus on method performance expectations.

 

SMPRs are codified and published in the Journal of AOAC INTERNATIONAL and the Official Methods of Analysis.

For more information or to participate, visit International Stakeholder Panel on Alternative Methods or contact Krystyna McIver, executive for scientific business development, at kmciver@aoac.org.

For more information on AOAC’s OA Program and/or working group initiative, visit Organizational Affiliates or contact Krystyna McIver at kmciver@aoac.org; Dawn Frazier at dfrazier@aoac.org; or Alicia Meiklejohn at ameiklejohn@aoac.org.