SPIFAN Working Group to Begin Standards Development Activities for 2- and 3-MCPD and GE in Finished Infant Formula Products

Standards development activities will be introduced at the AOAC Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN) meeting on March 15, 2017, during the AOAC Mid-Year Meeting in Gaithersburg, Maryland, USA, for 2-monochloro-1,2-propanediol (2-MCPD), 3-monochloro-1,2-propanediol (3-MCPD), and glycidyl esters (GE) in infant formula. The project is supported by the Infant Nutrition Council of America (INCA), an industry trade association of global infant formula manufacturers, including Abbott Nutrition, Danone, FreislandCampina, Nestlé, and Perrigo Nutritionals.

SPIFAN stakeholders have been following global activities, including those at the 83rd meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), to assess the possible presence of 2- and 3-MCPD and GE in infant formula. Scientific and regulatory bodies in the United States, Europe, and elsewhere are studying finished infant formula products, exploring possible mitigation activities, and considering steps to address the possible presence of 2- and 3-MCPD and GE in these products. There is currently no validated method of analysis for determination of 2-and 3-MCPD and GE in infant formula, and this new SPIFAN project is expected to address the method need.

During the upcoming SPIFAN meeting, the working group chair will present the background, issues and needs, analytical challenges, technical and regulatory requirements, and gaps in existing methodology for 2- and 3-MCPD and GE in finished infant formula products. A draft fitness-for-purpose statement will be proposed and deliberated by SPIFAN for possible endorsement.

Immediately following the stakeholder panel meeting, the working group is scheduled to begin drafting Standard Method Performance Requirements (SMPRs®), which define minimum criteria that candidate methods are expected to meet. The working group will continue to meet by teleconference throughout the spring and summer. Draft SMPRs® are anticipated to be reviewed by SPIFAN for possible approval on September 23, 2017, during the AOAC Annual Meeting and Exposition in Atlanta, Georgia, USA. Approved SMPRs® are codified and published by AOAC INTERNATIONAL.

Click here to register for the March 15 SPIFAN meeting or visit the AOAC Mid-Year Meeting website. There is no registration fee associated with these meetings. For more information, or if you would like to participate in the AOAC SPIFAN MCPD/GE Working Group or AOAC SPIFAN activities, contact Alicia Meiklejohn, director for scientific business development, at ameiklejohn@aoac.org or visit www.aoac.org.