Call for Methods: Vitamin C

AOAC INTERNATIONAL (AOAC) invites method developers to submit methods for consideration and possible evaluation through the AOAC Official Methods^SM program. Prospective methods must be able to determine Vitamin C in all forms of infant formula, follow-up formula, baby food, adult/pediatric formula, complementary food supplements, nutritional supplements for pregnant women and nursing mothers, and sports nutrition food. 

For the purpose of this call for methods, vitamin C is defined as the sum of L-ascorbic acid or its salts, and dehydro ascorbic acid. Reported as vitamin C (L-ascorbic acid) according to the draft Standard Method Performance Requirements (SMPR^®). D-ascorbic acid (erythorbic acid) and ascorbyl palmitate are excluded from the definition of vitamin C for the purposes of this Call for Methods. 

Access the Draft SMPR >

Method Eligibility

The objective of this project is to select, evaluate, and validate reference methods that can be used for dispute resolution. Acceptable methods must be reliable and reproducible when used by trained analysts in accredited laboratories.

Reference the draft SMPR for definitions of the various applicable commodities and the proposed method validation requirements for parameters such as analytical range, limit of quantitation, recovery, repeatability and reproducibility, system suitability and reference materials. Any analytical technique that meets the method performance requirements is acceptable.

Interested method developers must provide their method and data demonstrating that the method can meet the performance requirements.

AOAC Method Submission Requirements and Deadlines

Method authors may submit methods for review to the Official Methods of Analysis℠ (OMA) program.

• Candidate methods must be submitted in AOAC OMA format and the data submitted as a manuscript in Journal of AOAC INTERNATIONAL format. No exceptions. Please see the Guidelines for Method Authors.
• Full single laboratory validation required followed by a reproducibility study.
• Application fees apply for rapid commercial proprietary methods only.

Submit your method

Submit your method(s) for First or Final Action consideration. (Email submissions will not be accepted).

For general AOAC Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN) information or comments, contact Delia Boyd, Senior Manager at [email protected] or 301-924-7077, ext. 126.