November 10, 2022

DEADLINE:  CLOSED

AOAC Official Methods of Analysis℠ (OMA) Program

Determination of Fatty Acids which are esterified at the SN-2 position (beta) of the triacylglycerol molecules in infant formula, adult/pediatric formula and select milk and milk products

AOAC INTERNATIONAL (AOAC) invites method developers to submit methods for consideration and possible evaluation through the AOAC Official MethodsSM program. Prospective methods must be able to measure the amount of the fatty acids which are esterified at the sn-2 position (beta) of the triacylglycerol (TAG) molecules in all forms of infant formula and adult/pediatric nutritionals.  Methods with an expanded applicability to select milk and milk product samples as specified in TABLE 1 are highly encouraged for submission.

For the purpose of this call for methods, methods that quantitate the fatty acids which are esterified at the sn-2 position (beta) of the triacylglycerol (TAG) molecules in all forms of infant formula and adult/pediatric nutritionals. The method is applicable to infant formula and adult/pediatric nutritionals containing C4–C24 saturated and unsaturated fatty acids according to the published Standard Method Performance Requirements (SMPR®), AOAC SMPR 2022.004.    

Access the SMPR

SELECT MILK AND MILK PRODUCT SAMPLES

In collaboration with ISO/TC 34/SC 5 (Milk and milk products) and the International Dairy Federation (IDF), AOAC invites method developers to submit methods for the determination of fatty acids which are esterified at the sn-2 position (beta) of the triacylglycerol (TAG) molecules in both infant formula (according to the SMPR) and in the milk and milk product samples of interest to ISO/TC 34/SC 5 and IDF (provided samples can be analyzed during an MLT of the method) in TABLE 1.

TABLE 1 – Milk and milk product samples
Infant formula 1NIST 1848b (milk based)
Infant formula 2NIST 1869 (milk/whey/soy based)
Infant formula 4NIST 8261 (high protein)
Infant formula 6Infant formula with OPO ingredient
Infant formula 7Infant formula with milk fat ingredient
Whole milk powderNIS 1549a
AMF Anhydrous milk fatC4-20

Method Eligibility

The intended use of the method determined to meet the SMPR and fulfill the ERP recommendations is for Reference Method for Dispute Resolution as designated by Codex as Type II status for bovine A1 and A2 beta-casein.  Acceptable methods must be reliable, repeatable, and ultimately reproducible when used by trained analysts in accredited laboratories. 

Reference the draft SMPR for definitions and the proposed method validation requirements for parameters such as analytical range, limit of quantitation, recovery, repeatability and reproducibility, system suitability and reference materials.  Any analytical technique that meets the method performance requirements is acceptable.

Interested method developers must provide their method and data demonstrating that the method can meet the SMPR requirements for infant formula and adult/pediatric formula and for those methods with an expanded applicability, sufficient data is required to demonstrate satisfactory method performance for determining fatty acids which are esterified at the sn-2 position (beta) of the triacylglycerol (TAG) molecules  in infant formula, adult/pediatric formula and selected milk and milk product samples as indicated in TABLE 1.

AOAC Method Submission Requirements and Deadlines

Method authors may submit methods for review to the Official Methods of Analysis℠ (OMA) program.

Official Methods of Analysis (OMA) Program

  • Candidate methods must be submitted in AOAC OMA format, and the data submitted as a manuscript in Journal of AOAC INTERNATIONAL format. No exceptions.  Please see the Access to Method Submission Form below as it contains information on requirements for submission, including format information and method safety.
  • Full single laboratory validation required followed by a reproducibility study.
  • Application fees apply for rapid commercial proprietary methods only.
  • Methods and manuscripts must be submitted by specified deadlines.

DEADLINE:  ONGOING UNTIL FURTHER NOTICE

This Call for Methods will remain open into 2023. Future Analytical Methods Week method submission deadlines will be added to this call as soon as they are available.

Submit Your Method

Submit your method(s) for First Action status consideration. (Email submissions will not be accepted).

INFORMATION ON METHOD SUBMISSIONS:

For general information or comments on the Official MethodsSM Program, contact Deborah McKenzie at [email protected].

METHOD SUBMISSION APPLICATION:

For general questions on submitting methods for infant formula and adult nutritionals, contact Delia Boyd at [email protected].

Access SMPR

Click below to view Standard Method Performance Requirements (SMPR):

AOAC 2022.004– Standard Method Performance Requirements for Determination of fatty acids which are esterified at the sn-2 position (beta) of the triacylglycerol (TAG) molecules in Infant Formula and Adult/Pediatric Formula.