Newly Updated Method Validation Training Course

Friday, March 8, 2024 – 8:30 AM – 3:30 PM EST

This live training course reviews the technical validation requirements and processes of the Performance Tested Methods^SM and Official Methods of Analysis^SM programs. The course will include breakout sessions covering the technical requirements for microbiology methods and chemistry methods.

Course Contents

1. AOAC INTERNATIONAL Standards and Conformity Assessment
   1. Standards
      1. Guidelines – AOAC and others
      2. Standard Method Performance Requirements (SMPRs)
         1. How to find an SMPR
         2. Contents/format of an SMPR
      3. Regulations
   2. PTM
      1. Process flowchart
      2. Roles and responsibilities
      3. Searchable database
         1. How to find a method
         2. Contents/format of a certificate
   3. OMA
      1. Process flowchart
      2. Roles and responsibilities
      3. OMA Compendium
         1. How to find a method
         2. Contents/format of a method
2. Method Validation
   1. Introduction to Validation
      1. Why and when to validate?
      2. Validation vs Verification
   2. Method Parameters
      1. Qualitative
      2. Quantitative
      3. Conf
      4. ID
   3. Selectivity testing
      1. Microbiology
      2. Chemistry
   4. Calibration curves
      1. Regression models
      2. Evaluation of regression model
      3. Quantitation by AI modeling
      4. Microbiology
         1. Spiked
         2. Naturally contaminated
      5. Chemistry
         1. Matrix contaminants
            1. Spiked
            2. Fortified
            3. Incurred
         2. Matrix components
   5. Study designs and analysis
   6. Data analysis and interpretation
      1. Outliers
      2. AOAC Statistical Workbooks
      3. Claims

Target Attendees

• Method developers
• Independent laboratories
• Candidates for AOAC Expert Reviewers or Volunteer Experts

Learning Outcomes

Method developers: 

• Better understanding of AOAC conformity assessment programs and processes
• Improved study designs meeting AOAC and AOACRI requirements
• More concise data collection, and therefore, faster PTM and OMA approvals

Independent laboratories:

• Part of qualification as an AOACRI Independent Laboratory 
• Improved chances for selection for AOACRI studies and OMA collaborative studies
• Better understanding of technical requirements and processes for performing studies

Candidates for AOAC Expert Reviewers:

• Better understanding of AOAC conformity assessment programs and processes
• Better understanding of current practices, statistics, and acceptance criteria
• Improved chances for selection as an Expert Reviewer

Trainings are to be held in person at the AOAC 2024 Midyear Meeting. Additional fees required for meeting registration.

Training Course Fees

Member Fee	Non-Member Fee
$699	$799