Dr. Yang Zhao is a Pharmacologist in the Division of Toxicology, Office of Chemistry and Toxicology, within the Human Foods Program of the United States Food and Drug Administration (FDA). He has extensive expertise in LC/MS-based method development and validation for a wide range of compounds across diverse sample types, including biosamples, pharmaceuticals, foods, botanicals, herbal products, and dietary supplements.
Dr. Zhao’s current research focuses on developing advanced LC/MS-based analytical methodologies to detect food-related toxins in various cell culture media. These methodologies have been successfully applied to samples generated in predictive toxicity testing systems, supporting the FDA’s mission to ensure food safety.
With over 15 years of hands-on experience in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and tandem MS techniques, Dr. Zhao has developed a comprehensive understanding of method validation guidelines, including the ICH M10 Bioanalytical Method Validation and Study Sample Analysis guidance, as well as the AOAC International Guidelines for Single-Laboratory Validation of Chemical Methods for Dietary Supplements and Botanicals.
In addition to his research, Dr. Zhao has served as a peer reviewer for more than 20 scientific journals. He has authored over 60 peer-reviewed publications, which have collectively garnered more than 1,600 citations, reflecting an h-index of 24.
