Resource Description

Guidelines for the Use of AOAC Voluntary Consensus Standards

Published February 1, 2012

Guidelines for Standard Method Performance Requirements

Published 2016

Interlaboratory Study Workbook – Blind Replicates

Last revised 2012

Binary Data Interlaboratory Study Workbook

Last revised 2013

Format for AOAC Official Methods of Analysis

Last revised October 2013

Example of a Single Lab Validation Study

Example of a Single Lab Validation Study

Published January 30, 2004 Method for the Determination of Beta-Carotene in Supplements and Raw Materials by Reversed-Phase Liquid Chromatography: Single Laboratory Validation

Published January 30, 2004 Method for the Determination of Beta-Carotene in Supplements and Raw Materials by Reversed-Phase Liquid Chromatography: Single Laboratory Validation

Method Safety & Risk Assessment Guide

Method Safety & Risk Assessment Guide

Last revised October 2013

Last revised October 2013

Circular A-119 Revised

Circular A-119 Revised

Published February 10, 1998 Federal Participation in the Development and Use of Voluntary Consensus Standards and in Conformity Assessment Activities

Published February 10, 1998 Federal Participation in the Development and Use of Voluntary Consensus Standards and in Conformity Assessment Activities

AOAC Standard Protocol (SP) 2025.001 to Accompany AOAC SMPR 2025.002

AOAC Standard Protocol (SP) 2025.001 to Accompany AOAC SMPR 2025.002

Standard Protocol (SP) for Single and Independent Laboratory Validation of Methods for Detection of Benzodiazepines, Fentanyl, Medetomidine, Nitazenes, and Xylazine in Selected Drug Product Solids, Liquids, and Residues to Accompany […]

Standard Protocol (SP) for Single and Independent Laboratory Validation of Methods for Detection of Benzodiazepines, Fentanyl, Medetomidine, Nitazenes, and Xylazine in Selected Drug Product Solids, Liquids, and Residues to Accompany […]

AOAC SMPR® 2025.002

AOAC SMPR® 2025.002

Standard Method Performance Requirements (SMPRs®) for Detection of Benzodiazepines, Fentanyl, Medetomidine, Nitazenes, and Xylazine in Selected Drug Product Solids, Liquids, and Residues

Standard Method Performance Requirements (SMPRs®) for Detection of Benzodiazepines, Fentanyl, Medetomidine, Nitazenes, and Xylazine in Selected Drug Product Solids, Liquids, and Residues

AOAC SMPR® 2022.006

AOAC SMPR® 2022.006

Standard Method Performance Requirements (SMPRs®) for Acrylamide in Potato Products, Baby Food, Bread, Other Cereal and Bakery Products, Cocoa Products, Coffee, Tea, Herbs and Spices (Including Their Extracts and Mixtures), […]

Standard Method Performance Requirements (SMPRs®) for Acrylamide in Potato Products, Baby Food, Bread, Other Cereal and Bakery Products, Cocoa Products, Coffee, Tea, Herbs and Spices (Including Their Extracts and Mixtures), […]

AOAC SMPR® 2024.001

AOAC SMPR® 2024.001

Standard Method Performance Requirements (SMPRs®) for Selected Pesticides in Color Additives from Crop-Based Sources

Standard Method Performance Requirements (SMPRs®) for Selected Pesticides in Color Additives from Crop-Based Sources

34 New SMPRs and 16 Official Methods for Dietary Supplements

34 New SMPRs and 16 Official Methods for Dietary Supplements

Reprinted from Inside Laboratory Management, January-February 2019

Reprinted from Inside Laboratory Management, January-February 2019

AOAC SMPR® 2023.005

AOAC SMPR® 2023.005

Standard Method Performance Requirements (SMPRs®) for Determination of Heavy Metals in Cannabis-Containing Beverages

Standard Method Performance Requirements (SMPRs®) for Determination of Heavy Metals in Cannabis-Containing Beverages

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    July/August 2026 Issue of ILM Now Available Online

    August 27, 2026

    The July/August 2026 issue of Inside Laboratory Management (ILM)is now available online for members only. The cover feature is on Revamping and Modernizing AOAC Official MethodsSM Program. AOAC is implementing a future-oriented […]

    Chemistry, Contaminants

    Public Comment: Total Fluorine & TOF SMPRs

    August 26, 2026

    The AOAC PFAS Program Total Organic Fluorine Working Group completed its drafting and review of the Total Fluorine and Total Organic Fluorine in Food Packaging Materials SMPRs and is now […]

    Chemistry, Contaminants, Methods & Standards, OMA

    Call for Experts: PFAS in Food Contact Materials

    August 26, 2026

    AOAC Official Methods of AnalysisSM (OMA) program is currently seeking subject matter experts in PFAS analysis and food contact materials to serve as expert review panel (ERP) members to evaluate […]

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    Call for Methods: Molecular Weight Distribution

    August 26, 2026

    DEADLINE:  Friday, February 26, 2027 Characterization of Molecular Weight Distribution in Dairy Protein Hydrolysates AOAC INTERNATIONAL (AOAC) invites method developers to submit methods for First Action consideration and possible evaluation through […]